Oliver D Howes Selected Research

Dihydroxyphenylalanine (Dopa)

6/2021	Correction: Striatal dopaminergic alterations in individuals with copy number variants at the 22q11.2 genetic locus and their implications for psychosis risk: a [18F]-DOPA PET study.
5/2021	Striatal dopaminergic alterations in individuals with copy number variants at the 22q11.2 genetic locus and their implications for psychosis risk: a [18F]-DOPA PET study.
1/2021	Dopamine dysregulation in psychotic relapse after antipsychotic discontinuation: an [18F]DOPA and [11C]raclopride PET study in first-episode psychosis.
11/2019	Frontostriatal functional connectivity and striatal dopamine synthesis capacity in schizophrenia in terms of antipsychotic responsiveness: an [18F]DOPA PET and fMRI study.
1/2019	The effect of a genetic variant at the schizophrenia associated AS3MT/BORCS7 locus on striatal dopamine function: A PET imaging study.
12/2017	A Test of the Transdiagnostic Dopamine Hypothesis of Psychosis Using Positron Emission Tomographic Imaging in Bipolar Affective Disorder and Schizophrenia.
3/2017	Presynaptic Dopamine Capacity in Patients with Treatment-Resistant Schizophrenia Taking Clozapine: An [18F]DOPA PET Study.
7/2013	Dopaminergic function in the psychosis spectrum: an [18F]-DOPA imaging study in healthy individuals with auditory hallucinations.
11/2012	Dopamine synthesis capacity in patients with treatment-resistant schizophrenia.
11/2012	Transition to psychosis associated with prefrontal and subcortical dysfunction in ultra high-risk individuals.

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Oliver D Howes Research Topics

Disease

83	Schizophrenia (Dementia Praecox) 11/2022 - 02/2004
58	Psychotic Disorders (Schizoaffective Disorder) 11/2022 - 03/2004
16	Treatment-Resistant Schizophrenia 12/2022 - 11/2012
8	Mental Disorders (Mental Disorder) 05/2022 - 11/2013
6	Inflammation (Inflammations) 01/2021 - 01/2019
4	Prodromal Symptoms 01/2018 - 01/2009
3	Autism Spectrum Disorder 01/2021 - 01/2018
3	Hallucinations (Hallucination) 01/2020 - 07/2013
3	Substance-Related Disorders (Drug Abuse) 01/2019 - 03/2010
2	Paranoid Schizophrenia (Delusional Disorder) 07/2022 - 10/2020
2	Bipolar Disorder (Manic Depressive Psychosis) 01/2021 - 12/2017
2	Weight Gain 01/2020 - 01/2020
2	Chronic Disease (Chronic Diseases) 03/2017 - 05/2016
2	Insulin Resistance 03/2017 - 02/2004
2	Major Depressive Disorder (Major Depressive Disorders) 11/2015 - 11/2013
2	Osteoporosis 01/2012 - 06/2005
1	Cerebral Cortical Thinning 01/2022
1	Hypertriglyceridemia 12/2021
1	COVID-19 01/2021
1	Infections 01/2021
1	Body Weight (Weight, Body) 01/2020
1	Parkinson Disease (Parkinson's Disease) 01/2020
1	Cognitive Dysfunction 10/2019

Drug/Important Bio-Agent (IBA)

60	Dopamine (Intropin)FDA LinkGeneric 07/2022 - 03/2004
41	Antipsychotic Agents (Antipsychotics)IBA 06/2022 - 10/2004
19	Glutamic Acid (Glutamate)FDA Link 10/2021 - 02/2008
14	Clozapine (Clozaril)FDA LinkGeneric 12/2022 - 02/2004
13	Dihydroxyphenylalanine (Dopa)IBA 06/2021 - 12/2008
10	Pharmaceutical PreparationsIBA 12/2022 - 03/2004
8	Biomarkers (Surrogate Marker)IBA 12/2021 - 01/2009
8	Proteins (Proteins, Gene)FDA Link 10/2021 - 01/2016
6	Ketamine FDA LinkGeneric 11/2022 - 01/2013
6	Glucose (Dextrose)FDA LinkGeneric 12/2021 - 02/2004
6	Protons (Proton)IBA 01/2021 - 10/2010
5	N-Methyl-D-Aspartate Receptors (NMDA Receptors)IBA 11/2022 - 05/2014
5	gamma-Aminobutyric Acid (GABA)IBA 01/2021 - 01/2018
4	Polytetrafluoroethylene (Teflon)FDA Link 01/2021 - 12/2017
4	Biological ProductsIBA 01/2020 - 08/2015
3	Dopamine Receptors (Dopamine Receptor)IBA 01/2021 - 10/2011
3	Glycoproteins (Glycoprotein)IBA 01/2021 - 01/2020
3	RacloprideIBA 01/2021 - 03/2010
3	Messenger RNA (mRNA)IBA 01/2021 - 01/2019
3	ProlactinIBA 08/2012 - 06/2005
2	CannabidiolIBA 05/2022 - 01/2020
2	SEP-363856IBA 01/2022 - 12/2021
2	Dronabinol (THC)FDA LinkGeneric 01/2022 - 01/2020
2	C-Reactive ProteinIBA 12/2021 - 11/2019
2	LigandsIBA 12/2021 - 10/2021
2	Riluzole FDA LinkGeneric 01/2021 - 07/2019
2	Therapeutic UsesIBA 01/2021 - 01/2020
2	Amphetamine (Amfetamine)FDA LinkGeneric 01/2021 - 11/2019
2	Neurotransmitter Agents (Neurotransmitter)IBA 11/2020 - 02/2008
2	Serotonin (5 Hydroxytryptamine)IBA 01/2020 - 01/2020
2	CholesterolIBA 01/2020 - 12/2017
2	Triglycerides (Triacylglycerol)IBA 01/2020 - 12/2017
2	AutoantibodiesIBA 01/2019 - 02/2015
2	Alanine (L-Alanine)FDA Link 01/2019 - 12/2017
2	Serotonin Plasma Membrane Transport Proteins (Serotonin Transporter)IBA 01/2018 - 11/2015
2	Illicit Drugs (Recreational Drugs)IBA 11/2017 - 03/2014
2	Insulin (Novolin)FDA Link 03/2017 - 12/2006
2	fluorodopa F 18IBA 07/2013 - 01/2009
2	Levodopa (L Dopa)FDA LinkGeneric 07/2013 - 12/2008
1	Adenosine A2A Receptor (Adenosine A2A Receptors)IBA 11/2022
1	BI 425809IBA 01/2022
1	BI 409306IBA 01/2022
1	xanomelineIBA 01/2022
1	MK-8189IBA 01/2022
1	AdiponectinIBA 12/2021
1	Alkaline PhosphataseIBA 12/2021
1	N- benzyl- N- ethyl- 2- (7,8- dihydro- 7- methyl- 8- oxo- 2- phenyl- 9H- purin- 9- yl)acetamideIBA 10/2021
1	Prednisolone (Predate)FDA LinkGeneric 10/2021
1	3- iodo- 2- hydroxy- 6- methoxy- N- ((1- ethyl- 2- pyrrolidinyl)methyl)benzamideIBA 03/2021
1	GABA Receptors (GABA Receptor)IBA 01/2021
1	N-acetylaspartate (N-acetyl aspartate)IBA 01/2021
1	GABA-A Receptors (GABA(A) Receptor)IBA 01/2021
1	Serotonin 5-HT1 Receptor AgonistsIBA 01/2021
1	Caffeine (No Doz)FDA LinkGeneric 01/2021
1	brexpiprazoleIBA 01/2020
1	cariprazineIBA 01/2020
1	Lurasidone Hydrochloride FDA Link 01/2020
1	Olanzapine (Zyprexa)FDA Link 01/2020
1	Amisulpride (Solian)IBA 01/2020
1	Dextroamphetamine (Dexedrine)FDA LinkGeneric 01/2020
1	Haloperidol (Haldol)FDA LinkGeneric 01/2020
1	HDL CholesterolIBA 01/2020
1	LDL CholesterolIBA 01/2020
1	Adrenergic Receptors (Adrenergic Receptor)IBA 01/2020
1	Somatostatin (Somatotropin Release-Inhibiting Factor)IBA 01/2020
1	Cholinergic Agents (Cholinergics)IBA 01/2020
1	ParvalbuminsIBA 12/2019
1	Transforming Growth Factors (Transforming Growth Factor)IBA 11/2019
1	Interleukin-6 (Interleukin 6)IBA 11/2019
1	InterferonsIBA 11/2019
1	Interleukin-17 (Interleukin 17)IBA 11/2019
1	CytokinesIBA 11/2019
1	carfentanil (carfentanyl)IBA 10/2019
1	mu Opioid Receptors (mu Opioid Receptor)IBA 10/2019
1	Inositol (Myoinositol)IBA 01/2019

Therapy/Procedure

2	Therapeutics 01/2021 - 10/2004
1	Secondary Prevention 01/2020